Showing posts with label Mouse Models. Show all posts
Showing posts with label Mouse Models. Show all posts

Wednesday, November 16, 2011

The limitations of laboratory animals in biomedicine

There is a very interesting take in Slate on the reliance of Mouse Models in biomedical science. You can see the temptation in a fast growing animal that elicits limited sympathy from the general public. But the concern with missing key drugs is real -- especially when the diseases in mice operate differently than in humans.

But the real kicker was the discovery that control mice are overfed, under-stimulated and obese. This puts an entirely new spin on studies that restrict caloric intake. They may be saying that eating a normal diet is life enhancing and not caloric restriction. These sorts of blind alleys can have enormous consequences.

Go and read -- it is worth it.